Research progress of non-coding RNA in hepatic ischemia-reperfusion injury
10.3760/cma.j.issn.1007-8118.2020.01.019
- VernacularTitle:非编码RNA在肝脏缺血再灌注损伤中的研究进展
- Author:
Shilong ZHANG
1
;
Zanjie FENG
;
Cijun PENG
;
Weidong GAO
;
Yuling DUAN
;
Guoxin FAN
Author Information
1. 遵义医科大学附属医院肝胆外科
- Keywords:
Reperfusion injury;
Liver;
Non-coding RNA;
MicroRNA;
Small interfering RNA
- From:
Chinese Journal of Hepatobiliary Surgery
2020;26(1):72-75
- CountryChina
- Language:Chinese
-
Abstract:
Hepatic ischemia-reperfusion injury (HIRI) is the main cause of liver damage and even multiple organ failure after complex liver surgery.When liver ischemia reperfusion occurs,the non-coding RNAs in the liver tissue is dysregulated and part of the non-coding RNAs with abnormal expression is involved in HIRI regulation.Non-coding RNAs to may be the intervention target for reducing HIRI.This article summarized the types and related functions of non-coding RNAs,the role of different non-coding RNAs in HIRI,and the interconnections between various non-coding RNAs in HIRI.
