Clinical observation of hot-wet compression with Xiaohua ointment for acne mastitis in mass stage
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3760/cma.j.cn431274-20200113-00037
   		
        
        	
        		- VernacularTitle:消化膏湿热敷治疗粉刺性乳痈僵块期的临床观察
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Na FU
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Peiwen LYU
			        		
			        		;
		        		
		        		
		        		
			        		Dongxiao ZHANG
			        		
			        		;
		        		
		        		
		        		
			        		Wenjie ZHAO
			        		
			        		;
		        		
		        		
		        		
			        		Qiao HUANG
			        		
			        		;
		        		
		        		
		        		
			        		Hao DONG
			        		
			        		;
		        		
		        		
		        		
			        		Yujian SUN
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. 首都医科大学附属北京中医医院乳腺科 100010
			        		
		        		
	        		
        		 
        	
        	
        	
        	
            
            
            	- From:
	            		
	            			Journal of Chinese Physician
	            		
	            		 2020;22(8):1176-1179
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
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		        	Abstract:
			       	
			       		
				        
				        	Objective:To observe the clinical effects of hot-wet compression with Xiaohua ointment for acne mastitis in mass stage and its impacts on humoral immune function and inflammation.Methods:85 cases of patients with acne mastitis in mass stage treated in our hospital from January 2018 to January 2019 were selected as the research objects and randomly divided into control group (42 cases) and observation group (43 cases). The control group taken Tuoli xiaodu powder and external use of purple detumescence cream, and the observation group received hot-wet compression with Xiaohua ointment additionally. All treated for 30 days. The clinical efficacy, symptom scores, breast mass size, humoral immune indexes, C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) were compared, and the adverse reactions were recorded.Results:After treatment, the humoral immune indexes of the two groups had no significant change ( P>0.05), but the pain score, breast tumor size, mass score, CRP and ESR were significantly decreased than those before treatment ( P<0.05); compared with the control group, the pain score, breast tumor size and mass score in the observation group were significantly lower than those in the control group ( P<0.05). The total effective rate of the observation group was 83.7%, which was significantly higher than 59.5% of the control group ( P<0.05). There were no obvious adverse reactions in both groups. Conclusions:Hot-wet compression with Xiaohua ointment is effective and safe for patients with acne mastitis in mass stage, and could improve their inflammation.