Therapeutic effect of Bletilla Striata polysaccharide cream combined with Honghua Xiaoyao tablet on chloasma
10.3760/cma.j.issn.1008-6706.2020.23.008
- VernacularTitle:白及多糖乳膏联合红花逍遥片治疗黄褐斑的疗效观察
- Author:
Fang CHEN
1
;
Rui WU
;
Wentao LIU
;
Mingquan CHANG
Author Information
1. 湖北省，十堰市太和医院 湖北医药学院附属医院药学部 442000
- From:
Chinese Journal of Primary Medicine and Pharmacy
2020;27(23):2851-2854
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe the clinical efficacy of oral administration of Bletilla Striata polysaccharide cream combined with Honghua Xiaoyao tablet in the treatment of chloasma.Methods:A total of 220 female patients with chloasma treated in the dermatology department of Taihe Hospital of Shiyan (Affiliated Hospital of Hubei Medical College) from January 2018 to October 2018 were enrolled.The patients were divided into treatment group and control group by random number table method, with 110 cases in each group.The treatment group was treated with Bletilla Striata polysaccharide cream, 1 time in the morning and evening.The control group was treated with Qianbai cream, 1 time in the morning and evening, and the two groups were treated with Honghua Xiaoyao tablets, each time 1.17g, 3 times a day.One month was a course of treatment, a total of 3 courses of treatment.The effect was observed by skin lesion score, effective rate and adverse reaction.Results:After 3 courses of treatment, the skin lesion score and effective rate in the treatment group were (0.93±0.31)points, 84.55%(93/110), respectively, which in the control group were (1.39±0.44)points, 65.45%(71/110), respectively, the difference between the two groups was statistically significant( t=9.901, χ 2=11.594, all P<0.05). The incidence of adverse reactions in the treatment group was significantly lower than that in the control group(χ 2=4.053, P<0.05). Conclusion:The efficacy of Bletilla Striata polysaccharide cream combined with Honghua Xiaoyao tablet in the treatment of chloasma is better than Qianbai cream, and the incidence of adverse reaction is low.
