Retrospective analysis of enteral feeding of premature infants with gestational age less than 32 weeks
10.3760/cma.j.cn101070-20190820-00770
- VernacularTitle:胎龄小于32周早产儿肠内喂养情况回顾性分析
- Author:
Ying LI
1
;
Fan WU
;
Qiliang CUI
Author Information
1. 广州医科大学附属第三医院新生儿科 510150
- From:
Chinese Journal of Applied Clinical Pediatrics
2020;35(23):1781-1785
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the status of enteral feeding and the incidence of feeding intolerance in premature infants less than 32 weeks of gestation age, as well as the difficulties during enteral feeding.Methods:A retrospective analysis was conducted on preterm infants less than 32 weeks of gestation age admitted to the Neonatal Intensive Care Unit of the Third Affiliated Hospital of Guangzhou Medical University from January to December 2018.The infants were divided into 2 groups: 76 cases in the feeding tolerance group, 45 males (59.2%, 45/76 cases), mean gestational age (29.43±1.42) weeks; 79 cases in the feeding intolerance group, 48 males (60.8%, 48/79 cases), mean gestational age (29.16±1.60) weeks.The incidence of feeding intolerance was explored, and the enteral feeding, growth and main diagnosis as well as treatment during hospitalization between the 2 groups were compared.Results:(1) For preterm infants less than 32 weeks of gestation age, 92.9%(144/155 cases) of infants were given formula milk within 48 hours after birth, and 76.1% (118/155 cases) of infants were given formula milk within 24 hours after birth, the initial milk feeding volume of the 2 groups were [(12.24±4.37) mL/ (kg·d) vs.(11.23±4.88) mL/(kg·d), t= 0.812, P>0.05]. (2) The rate of milk volume increase in the feeding tolerance group and feeding intolerance group were [(8.69±4.30)mL / (kg·d) vs.(4.29±4.02) mL / (kg·d) in week 1; (8.43±0.45) mL / (kg·d) vs.(4.26±2.75) mL / (kg·d) in week 2, t=6.583, t′=13.294, all P<0.05)]. (3) The duration of achieving sufficient enteral feeding in the feeding tolerance and feeding intolerance group premature infant were[(20.55±9.66) d vs.(34.88±15.02) d, t=7.489, P<0.05]. (4) The feeding tolerance group had shorter hospital stay, more weight gain and lower incidence of extrauterine growth retardation than the feeding intolerance group.(5) The incidence of feeding intolerance was 50.9% (79/155 cases) in preterm infants less than 32 weeks of gestation age, delayed meconium excretion, blood transfusion, non-invasive mechanical ventilation, use of hormones, use of antibiotics for more than 2 weeks, bronchopulmonary dysplasia may be associated with feeding intolerance. Conclusion:Enteral feeding is not ideal for preterm infants less than 32 weeks of gestation age, and the incidence of feeding intolerance is high.The feeding plan of medical staff needs to be improved.
