Micropapillary Lung Cancer with Breast Metastasis Simulating Primary Breast Cancer due to Architectural Distortion on Images.
10.3348/kjr.2012.13.2.249
- Author:
Kyungran KO
1
;
Jae Yoon RO
;
Eun Kyung HONG
;
Seeyeon LEE
Author Information
1. Department of Diagnostic Radiology, Center for Breast Cancer, National Cancer Center, Goyang 410-769, Korea.
- Publication Type:Case Reports
- Keywords:
Metastasis;
Breast images;
Lung cancer;
Micropapillary carcinoma
- MeSH:
Adenocarcinoma/drug therapy/*secondary;
Antineoplastic Combined Chemotherapy Protocols/therapeutic use;
Biopsy, Needle;
Bone Neoplasms/secondary;
Breast Neoplasms/drug therapy/*secondary;
Diagnosis, Differential;
Female;
Humans;
Lung Neoplasms/*pathology;
Lymphatic Metastasis;
Mammography;
Middle Aged;
Neoplasm Staging;
Tomography, X-Ray Computed;
Ultrasonography, Mammary
- From:Korean Journal of Radiology
2012;13(2):249-253
- CountryRepublic of Korea
- Language:English
-
Abstract:
A 47-year-old Korean woman with right middle lobe lung adenocarcinoma, malignant pleural effusion, and multiple lymph node and bone metastases, after three months of lung cancer diagnosis, presented with a palpable right breast mass. Images of the right breast demonstrated architectural distortion that strongly suggested primary breast cancer. Breast biopsy revealed metastatic lung cancer with a negative result for estrogen receptor (ER), progesterone receptor (PR) and mammaglobin, and a positive result for thyroid transcription factor-1 (TTF-1). We present a case of breast metastasis from a case of lung cancer with an extensive micropapillary component, which was initially misinterpreted as a primary breast cancer due to unusual image findings with architectural distortion.
