Clinical application value of magnifying endoscopy combined with high frequency endoscopic ultrasonography in the diagnosis and recurrence monitoring of gastric mucosa-associated lymphoid tissue lymphoma
10.3760/cma.j.cn115356-20200207-00035
- VernacularTitle:放大内镜联合高频超声内镜在胃黏膜相关淋巴组织淋巴瘤诊断及复发监测中的临床应用价值
- Author:
Ting ZHANG
1
;
Jun XIAO
;
Yuhong ZHOU
;
Qide ZHANG
;
Shutang HAN
Author Information
1. 南京中医药大学附属江苏省中医院消化内镜中心 210029
- From:
Journal of Leukemia & Lymphoma
2020;29(6):346-349
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the clinical value of magnifying endoscopy and high frequency endoscopic ultrasonography (HFUS) in the diagnosis and recurrence monitoring of gastric mucosa-associated lymphoid tissue lymphoma (GML).Methods:A total of 15 patients with newly diagnosed GML in the Jiangsu Province Hospital of Chinese Medicine from October 2016 to October 2019 were collected. The general data, clinical manifestations, Lugano staging, gastroscope performance, magnifying endoscopic performance, HFUS performance and helicobacter pylori infection were retrospectively analyzed. The efficacy and follow-up were also analyzed.Results:The most common symptom of 15 patients with GML was upper abdominal discomfort, followed by weight loss and anemia. The frequent site of GML was the middle 1/3 of the stomach (10 cases) and the most common type was diffuse (8 cases). The positive helicobacter pylori were detected in 9 cases. The positive tree-like appearance (TLA) was found in 13 cases under magnifying endoscopy; after the treatment, 2 cases had positive TLA. The unclear 1-3 layer structure of gastric wall in lesions was observed by using HFUS, accompanied with hypoechoic alteration. After the treatment, HFUS reexamination showed that the 1-5 layer structure of gastric wall disappeared in one patient, the pathological results confirmed that GML transformed into diffuse large B-cell lymphoma.Conclusion:Magnifying endoscopy combined with HFUS has an important application value in therapeutic efficacy evaluation and recurrence monitoring of GML; HFUS may has a certain clinical value in the progress assessment of GML.
