Cellular composition and function of B-cell lymphoma
10.3760/cma.j.cn115356-20200420-00099
- VernacularTitle:B细胞淋巴瘤的细胞组成及作用
- Author:
Kefu WU
1
;
Guoguang ZHENG
;
Xiaotong MA
;
Yuhua SONG
Author Information
1. 中国医学科学院血液病医院（中国医学科学院血液学研究所） 实验血液学国家重点实验室 国家血液病临床医学研究中心，天津 300020
- From:
Journal of Leukemia & Lymphoma
2020;29(6):321-325
- CountryChina
- Language:Chinese
-
Abstract:
B-cell lymphomas are a group of highly heterogeneous malignancies. The phenotypes of different subtypes depend on the differentiation stage and genetic changes of B-cell, which reflects in the immunophenotype, karyotype and tumor microenvironment changes, especially the differences in the cellular composition of microenvironment. This article reviews the characteristics of B-cell lymphoma cells and the cellular composition of microenvironment, discusses the role of tumor microenvironment cells in the occurrence and development of B-cell lymphoma, which provides new ideas for clinical diagnosis and treatment.
