Progress of chimeric antigen receptor T-cell therapy in treatment of hematological malignancies
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3760/cma.j.issn.1009-9921.2019.12.000
   		
        
        	
        		- VernacularTitle:嵌合抗原受体T细胞疗法在恶性血液病治疗中的研究进展
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Huanying REN
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Xiuhua CHEN
			        		
			        		;
		        		
		        		
		        		
			        		Jing XU
			        		
			        		;
		        		
		        		
		        		
			        		Hongwei WANG
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. 山西医科大学第二医院血液病研究所 血液病分子诊疗山西省重点实验室,太原 030001
			        		
		        		
	        		
        		 
        	
        	
        	
        	
            
            
            	- From:
	            		
	            			Journal of Leukemia & Lymphoma
	            		
	            		 2020;29(5):310-312
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
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		        	Abstract:
			       	
			       		
				        
				        	Chimeric antigen receptor T-cell (CAR-T) therapy is effective in treating lymphoma and leukemia. A large number of basic and clinical studies have led to the rapid development of CAR-T therapy. This paper reviews the concept of CAR-T therapy, the application of CAR-T in hematologic diseases, and the problems and solutions of CAR-T.