Clinical diagnosis, staging, and therapeutic principles of liver cirrhosis
DOI:10.3969/j.issn.1001-5256.2021.01.004
- VernacularTitle:肝硬化的诊断、分期及治疗原则
- Author:
Yu WANG
1
;
Min WANG
;
Guanhua ZHANG
;
Fuliang HE
;
Xiaojuan OU
;
Jidong JIA
Author Information
1. Liver Research Center, Beijing Friendship Hospital, Capital Medical University
- Publication Type:Research Article
- Keywords:
Liver Cirrhosis;
Diagnosis;
Staging;
Therapeutics
- From:
Journal of Clinical Hepatology
2021;37(1):17-21
- CountryChina
- Language:Chinese
-
Abstract:
With in-depth studies on the pathogenesis, pathophysiology, treatment, and prognosis of liver cirrhosis in recent years, there have been great changes in staging and treatment concepts among scholars in China and globally. Besides the traditional staging system of compensated and decompensated liver cirrhosis, liver cirrhosis can be divided into five stages based on ascites, variceal bleeding, and severe infection, which highlights the features of this disease in different disease stages and this provides potential targets and basis for treatment. At present, the comprehensive management of liver cirrhosis, including etiological treatment, treatment targeting key pathogenesis and major complications, nutritional support, exercise guidance, and lifestyle adjustment (smoking cessation, alcohol withdrawal, and improvement of oral hygiene), is the key to delaying disease progression and improving prognosis, and liver transplantation remains the most effective approach for end-stage liver cirrhosis.
