Advances in Study on Pathogenesis of Irritable Bowel Syndrome
10.3969/j.issn.1008-7125.2020.06.001
- VernacularTitle: 肠易激综合征发病机制研究进展
- Author:
Xiucai FANG
1
Author Information
1. Department of Gastroenterology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
- Publication Type:Journal Article
- Keywords:
Enteric Nervous System;
Gut Microbiota;
Intestinal Mucosal Barrier;
Irritable Bowel Syndrome;
Pathogenesis
- From:
Chinese Journal of Gastroenterology
2020;25(6):321-325
- CountryChina
- Language:Chinese
-
Abstract:
The pathophysiological process of irritable bowel syndrome (IBS) is complex. Recent studies showed that alteration in gut microbiota, damage of intestinal mucosal barrier and increase of mucosal permeability due to inflammation, diet and stress, as well as abnormalities of enteric nervous system in both function and morphology play important roles in the development of IBS. In this article, the advances in studies on above mentioned pathogenic mechanisms of IBS were briefly summarized.
