Research progress and utilization strategy on alkaloid resource chemistry of Coptidis Rhizoma
10.7501/j.issn.0253-2670.2019.20.034
- VernacularTitle: 黄连生物碱类资源性化学成分研究进展与利用策略
- Author:
Nian-Yun YANG
1
Author Information
1. National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine, Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Jiangsu Plant Medicine Research and Development Center, Nanjing University of Chinese Medicine
- Publication Type:Journal Article
- Keywords:
Alkaloids;
Coptidis Rhizoma;
High value development of resource compounds;
Non-traditional medicinal tissues;
Resource chemistry;
Utilization strategy
- From:
Chinese Traditional and Herbal Drugs
2019;50(20):5080-5087
- CountryChina
- Language:Chinese
-
Abstract:
Coptidis Rhizoma is one of the staple traditional Chinese medicinal materails in China with long officinal history, and its alkaloids provide the most important sources of precursor compounds in innovative drug research, which has been the focus of industry attention. This paper emphasized the industry development and summarized the alkaloid resource chemical constituents in Coptidis Rhizoma, and the progress of resource chemical research on Coptidis Rhizoma based on quality evaluation, structure modification and industrial application of the alkaloids was analyzed. The attention to the high value development of resource compounds and the use of “non-traditional medicinal tissues” for the limited resource Coptidis Rhizoma were proposed. The utilization ways and strategies provide important reference for the comprehensive development and resource recycling of Coptidis Rhizoma.
