Research advances in the pathogenesis of alcoholic liver disease
DOI:10.3969/j.issn.1001-5256.2020.12.038
- VernacularTitle:酒精性肝病发病机制研究现状
- Author:
Ya WU
1
;
Yanru LI
;
Jizhuo YANG
;
Jianzhong YIN
;
Yuemei FENG
Author Information
1. School of Pubic Health, Kunming Medical University, Kunming 650500, China
- Publication Type:Research Article
- Keywords:
liver diseases, alcoholic;
oxidative stress;
gastrointestinal microbiome;
polymorphism, genetic
- From:
Journal of Clinical Hepatology
2020;36(12):2822-2825
- CountryChina
- Language:Chinese
-
Abstract:
Alcoholic liver disease (ALD) is a common cause of liver dysfunction and death due to liver-related diseases, which brings great harm to human health and social development. Many factors are involved in the development and progression of ALD, such as oxidative stress, change in gut microbiota, genetic variation, autophagy inhibition, and microRNAs. This article summarizes the mechanism of action of these factors in ALD, in order to provide a basis for the treatment of ALD and the discovery of new drug targets.
