Study on the factors affecting the degradation of niclosamide in the soil
10.16250/j.32.1374.2019169
- VernacularTitle:土壤中氯硝柳胺降解影响因素的研究
- Author:
Yue JIA
1
;
Yun-Tian XING
2
;
Jian-Rong DAI
2
;
Guo-Li QU
2
;
You-Sheng LIANG
2
Author Information
1. Jiangsu Institute of Parasitic Diseases, Key Laboratory of National Health Commission on Parasitic Disease Prevention and Control, Jiangsu Provincial Key Laboratory of Parasites and Vector Control Technology, Wuxi 214064, China; Liangxi Center for Disease Control and Prevention, Wuxi City, Jiangsu Province, China
2. Jiangsu Institute of Parasitic Diseases, Key Laboratory of National Health Commission on Parasitic Disease Prevention and Control, Jiangsu Provincial Key Laboratory of Parasites and Vector Control Technology, Wuxi 214064, China
- Publication Type:Journal Article
- Keywords:
Niclosamide;
Degradation;
Soil;
Half-life
- From:
Chinese Journal of Schistosomiasis Control
2020;32(6):559-564
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo investigate the factors affecting the degradation of niclosamide in the soil, so as to provide the evidence for the assessment of the environmental safety in the field snail control with niclosamide. MethodsA high performance liquid chromatography was established for the determination of niclosamide in the field. Then, the degradation of niclosamide was investigated in soils with different moistures (10%, 30%, 50%, 70% and 90%), temperatures [(15 ± 1), (25 ± 1), (35 ± 1) °C], initial concentrations (1, 5, 10 mg/kg) and in sterilized and non-sterilized soils. In addition, the degradation of niclosamide was fitted with the first-order kinetics equation, and the degradation half-life was calculated. Results The niclosamide residues gradually decreased over time in soils with different moistures, and a higher rate of degradation was seen in soils with a higher moisture. The degradation half-life of niclosamide reduced from 4.258 d in the soil with a 10% moisture to 2.412 d in the soil with a 90% moisture. The niclosamide residues gradually decreased over time in soils with different temperatures, and a higher rate of degradation was seen in soils with a higher temperature. The degradation half-life of niclosamide reduced from 4.398 d in the soil with a temperature of (15 ± 1) °C to 2.828 d in the soil with a temperature of (35 ± 1) °C. The degradation half-lives of niclosamide were 3.212, 3.333 d and 3.448 d in soils containing niclosamide at initial concentrations of 1, 5 mg/kg and 10 mg/kg, and > 30 d and 3.273 d in sterilized and non-sterilized soils. Multiple linear regression analysis revealed that soil microorganisms (P = 0.010), moisture (P = 0.000) and temperature (P = 0.002) affected the half-life of niclosamide degradation. Conclusions The degradation of niclosamide in soils fits the first-order kinetics equation, and presence of microorganisms, a high temperature and high moisture may accelerate the degradation of niclosamide in the soil.
