Epidemiological characteristics and interruption of 228 HBV positive pregnant women
10.3969/j.issn.1006-2483.2020.05.034
- VernacularTitle:228例HBV阳性孕妇流行病学特征及阻断分析
- Author:
Zan MAI
1
;
Jianhui FAN
2
;
Minjuan YE
2
Author Information
1. Department of Obstetrics and Gynecology, Guangzhou Eighth People's Hospital, Guangzhou, Guangdong 510060, China
2. Department of Obstetrics and Gynecology, the Third Affiliated Hospital of Sun Yat sen University, Guangzhou, Guangdong 510630, China
- Publication Type:Journal Article
- Keywords:
Hepatitis B virus;
pregnant women;
Epidemiology;
Mother-to-child transmission blocking;
Antiviral therapy
- From:
Journal of Public Health and Preventive Medicine
2020;31(5):131-134
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the epidemiological characteristics and interruption of 228 hepatitis B virus (HBV) positive pregnant women, and to provide more references for clinical education and treatment. Methods A total of 228 chronic HBV pregnant women underwent maternal-neonatal transmission blocking treatment in Third Affiliated Hospital of Sun Yat-sen University from January 2015 to April 2019 were enrolled. Self-designed follow-up questionnaires were used to collect pregnant women's data. Then the relationship of epidemiological characteristics and HBV-DNA load levels with the genotype, hepatitis B e antigen (HBeAg), and alanine aminotransferase (ALT) was analyzed, moreover, the prevention of mother-to-child transmission was also analyzed. Results A total of 228 HBV-positive pregnant women were mainly over 30 years old, with a family history of liver disease, low education level (
