Predictors of Ischemic Cardiomyopathy in Patients with Acute Myocardial Infarction who Underwent Percutaneous Coronary Intervention
10.3904/kjm.2020.95.3.188
- Author:
Hye Sook KIM
1
;
Myung Ho JEONG
;
Hyun Ju YOON
;
Yongcheol KIM
;
Seok-Joon SOHN
;
Min Chul KIM
;
Doo Sun SIM
;
Young Joon HONG
;
Ju Han KIM
;
Youngkeun AHN
;
Jae Young CHO
;
Kye Hun KIM
;
Jong Chun PARK
Author Information
1. The Heart Center of Chonnam National University Hospital, Gwangju, Korea
- Publication Type:1
- From:Korean Journal of Medicine
2020;95(3):188-200
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Background/Aims:Many patients with acute myocardial infarction (AMI) suffer from heart failure due to progressive ischemic left ventricular (LV) remodeling. This study investigated the predictors of ischemic cardiomyopathy (ICMP) in patients with AMI who underwent successful percutaneous intervention.
Methods:A total of 547 patients with AMI were divided into two groups: ICMP (n = 66, 67.1 ± 11.9 years, 78.8% males) and non-ICMP (n = 481, 62.5 ± 12.2 years, 70.1% males).
Results:On echocardiography, the LVEF was significantly decreased (41.7 ± 10.5 vs. 55.4 ± 10.3%, p < 0.001) but the LV end-diastolic (54.1 ± 7.2 vs. 49.3 ± 5.3 mm, p < 0.001) and systolic (42.1 ± 8.0 vs. 33.5 ± 6.0 mm, p < 0.001) dimensions significantly increased in the ICMP group compared with the non-ICMP group. According to multivariate logistic regression analysis, LVEF < 50% (odds ratio [OR] 8.722, 95% confidence interval [CI] 2.986–25.478, p < 0.001), LV end-diastolic dimension > 55 mm (OR 4.511, 95% CI 1.561–13.038, p = 0.005), and ratio of early mitral inflow velocity to mitral annular early diastolic velocity (E/e’) ≥ 15 (OR 3.270, 95% CI 1.168–9.155, p = 0.024) were independent predictors of ICMP development.
Conclusions:The present study demonstrates that a larger LV size, lower LV function, and increased E/e’ (≥ 15) were independent predictors of ICMP. Therefore, the development of ICMP should be carefully monitored in AMI patients with these features.
