- Author:
Haeju LEE
1
;
Ho Young HWANG
;
Suk Ho SOHN
;
Jae Woong CHOI
;
Jun-Bean PARK
;
Kyung Hwan KIM
;
Ki-Bong KIM
Author Information
- Publication Type:Clinical Research
- From:The Korean Journal of Thoracic and Cardiovascular Surgery 2020;53(5):285-290
- CountryRepublic of Korea
- Language:English
-
Abstract:
Background:This study was conducted to evaluate the hemodynamic performance and the incidence of prosthesis-patient mismatch (PPM) after aortic valve replacement (AVR) using bovine pericardial valves (Carpentier-Edwards Perimount Magana and Magna Ease).
Methods:In total, 216 patients (mean age, 70.0±10.5 years) who underwent AVR using stented bovine pericardial valves and had follow-up echocardiography between 3 months and 2 years (mean, 12.0±6.6 months) after surgery were enrolled. The implanted valve sizes were 19, 21, 23, and 25 mm in 32, 56, 99, and 29 patients, respectively.
Results:On follow-up echocardiography, the mean transvalvular pressure gradients for the 19-mm, 21-mm, 23-mm, and 25-mm valves were 13.3±4.4, 12.6±4.2, 10.5±3.9, and 10.2± 3.7 mm Hg, respectively. The effective orifice area (EOA) was 1.25±0.26, 1.54±0.31, 1.81±0.41, and 1.87±0.33 ㎠ , respectively. These values were smaller than those suggested by the manufacturer for the corresponding sizes. No patients had PPM, when based on the reference EOA. However, moderate (EOA index ≤0.85㎠ /㎡ ) and severe (EOA index ≤0.65 ㎠ /㎡ ) PPM was present in 56 patients (11.8%) and 9 patients (1.9%), respectively, when using the measured values.
Conclusion:Carpentier-Edwards Perimount Magna and Magna Ease bovine pericardial valves showed satisfactory hemodynamic performance with low rates of PPM, although the reference EOA could overestimate the true EOA for individual patients.

