Effects of a Portfolio-Mediterranean Diet and a Mediterranean Diet with or without a Sterol-Enriched Yogurt in Individuals with Hypercholesterolemia
10.3803/EnM.2020.35.2.298
- Author:
Yvelise FERRO
1
;
Elisa MAZZA
;
Mariantonietta SALVATI
;
Emma SANTARIGA
;
Salvatore GIAMPÀ
;
Rocco SPAGNUOLO
;
Patrizia DOLDO
;
Roberta PUJIA
;
Adriana COPPOLA
;
Carmine GAZZARUSO
;
Arturo PUJIA
;
Tiziana MONTALCINI
Author Information
1. Department of Health Science, University Magna Grecia, Catanzaro
- Publication Type:Original Article
- From:Endocrinology and Metabolism
2020;35(2):298-307
- CountryRepublic of Korea
- Language:English
-
Abstract:
Background:A growing number of functional foods have been proposed to reduce cholesterol levels and the Portfolio Diet, which includes a combination of plant sterols, fibres, nuts, and soy protein, reduces low density lipoprotein cholesterol (LDL-C) from 20% to 30% in individuals with hyperlipidaemia. In this pilot study, the aim was to investigate whether a Mediterranean Diet incorporating a new and simple combination of cholesterol-lowering foods, excluding soy and nuts (namely the Portfolio-Mediterranean Diet), would reduce LDL-C levels, in the short-term, better than a Mediterranean Diet plus a sterol-enriched yogurt or a Mediterranean Diet alone.
Methods:We retrospectively evaluated 24 individuals on a Portfolio-Mediterranean Diet and 48 matched individuals on a Mediterranean Diet with or without a sterol-enriched yogurt (24 each groups) as controls.
Results:At follow-up (after 48±12 days), we observed an LDL reduction of 21±4, 23±4, and 44±4 mg/dL in the Mediterranean Diet alone, Mediterranean Diet plus yogurt and Portfolio-Mediterranean Diet respectively (P<0.001).
Conclusion:A Portfolio-Mediterranean Diet, incorporating a new combination of functional foods such as oats or barley, plant sterols, chitosan, and green tea but not soy and nuts, may reduce LDL of 25% in the short term in individuals with hypercholesterolemia.
