Advances in research of protein kinase A in parasites: a review
10.16250/j.32.1374.2019236
- VernacularTitle:寄生虫蛋白激酶A 研究进展
- Author:
Jun-Jie FAN
1
;
Kai LI
1
;
Qing-Qing TAN
1
;
Wen-Qiao CAO
1
;
Bin YE
2
Author Information
1. Department of Pathogenic Biology, Chongqing Medical University, Chongqing 400016, China
2. Department of Pathogenic Biology, Chongqing Medical University, Chongqing 400016, China; Research Center for Molecular Medicine and Tumor, Chongqing Medical University, China
- Publication Type:Journal Article
- Keywords:
Protein kinase A;
Signaling pathway;
Parasite
- From:
Chinese Journal of Schistosomiasis Control
2020;32(5):537-541
- CountryChina
- Language:Chinese
-
Abstract:
Protein kinase A (PKA) is an important intracellular substance that regulates substance metabolism and biological functions, which exerts a wide range of biological effects through phosphorylation of specific serine/threonine residues in specific proteins. PKA plays an important role in the cAMP signaling pathway, and is involved in various life activities of parasites. Therefore, investigating the role of PKA in the life activities of parasites may provide insights into the development of novel anti-parasitic targets. The review mainly describes the structure and function of PKA and its role in life activities of parasites.
