Comparative analysis and study on component characteristics of inorganic elements in genuine Moutan Cortex and their differences from other areas.
10.19540/j.cnki.cjcmm.20200522.301
- Author:
Mao-Mao ZHU
1
;
Yun-Qing XIA
2
;
Liang FENG
3
;
Xiao-Bin JIA
3
Author Information
1. Nanjing Institute of Product Quality Inspection Nanjing 210023, China School of Traditional Chinese Pharmacy, China Pharmaceutical University Nanjing 211198, China.
2. School of Traditional Chinese Pharmacy, China Pharmaceutical University Nanjing 211198, China School of Pharmacy, Jiangsu University Zhenjiang 212013, China.
3. School of Traditional Chinese Pharmacy, China Pharmaceutical University Nanjing 211198, China.
- Publication Type:Journal Article
- Keywords:
Moutan Cortex;
genuine;
inorganic element;
structural characteristics of components
- MeSH:
Drugs, Chinese Herbal;
Paeonia;
Principal Component Analysis;
Quality Control;
Trace Elements
- From:
China Journal of Chinese Materia Medica
2020;45(14):3360-3368
- CountryChina
- Language:Chinese
-
Abstract:
Based on the theory of "component structure", the component structure characteristics of 17 inorganic elements in 20 batches of genuine Moutan Cortex and 12 batches of non-genuine Moutan Cortex were analyzed. The analytical method of inductively coupled plasma mass spectrometry(ICP-MS) for inorganic elements in Moutan Cortex was established, and the fingerprint of inorganic elements was drawn. Through correlation analysis and principal component analysis, the constituent elements of inorganic elements in Moutan Cortex were excavated, namely characteristic elements As, Cr, Pb, Se, K, Cu and Cd. The amount and the quantity relative ratio between the components of genuine and non-genuine Moutan Cortex samples were analyzed. It was found that the amount of characteristic elements in the bulk genuine Moutan Cortex samples was 0.33, 1.42, 1.33, 0.11, 4 385.78, 4.87, 0.49 mg·kg~(-1), with the quantity relative ratio of 1.00∶4.30∶4.03∶0.33∶13 290.24∶14.76∶1.48. The amount of characteristic elements in sub-packaged genuine Moutan Cortex was 0.24, 1.96, 0.36, 0.05, 5 122.01, 4.81, 0.05 mg·kg~(-1), with the quantity relative ratio of 1.00∶8.17∶1.50∶0.21∶21 341.71∶20.04∶0.21. The unique structural characteristics of inorganic elements in genuine Moutan Cortex are studied to provide a basis for the quality control and safety evaluation of Moutan Cortex.
