Expert consensus on Injection of Breviscapine in clinical practice.
	    		
		   		
		   			
		   		
	    	
    	 
    	10.19540/j.cnki.cjcmm.20200217.501
   		
        
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Yuan-Yuan LI
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Rong-Juan GUO
			        		
			        		
			        		
			        			2
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Yan-Ming XIE
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Ya-Ming LIN
			        		
			        		
			        		
			        			3
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Ye-Feng CAI
			        		
			        		
			        		
			        			4
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Jian-Jun ZHAO
			        		
			        		
			        		
			        			5
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Tao GUO
			        		
			        		
			        		
			        			6
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Ling ZHANG
			        		
			        		
			        		
			        			7
			        			
			        		
			        		
			        		
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences Beijing 100700, China.
			        		
			        			2. Dongfang Hospital, Beijing University of Chinese Medicine Beijing 100078, China.
			        		
			        			3. Yunnan Provincial Hospital of Traditional Chinese Medicine Kunming 650021, China.
			        		
			        			4. Guangdong Provincial Hospital of Chinese Medicine Guangzhou 100091, China.
			        		
			        			5. Affiliated Hospital of Changchun University of Traditional Chinese Medicine Changchun 130021, China.
			        		
			        			6. Fuwai Yunnan Cardiovascular Hospital Kunming 650101, China.
			        		
			        			7. School of Public Health, Capital Medical University Beijing 100015, China.
			        		
		        		
	        		
        		 
        	
        	
        	
        		- Publication Type:Journal Article
 
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		GRADE;
			        		
			        		
			        		
				        		Injection of Breviscapine;
			        		
			        		
			        		
				        		cerebrovascular disease;
			        		
			        		
			        		
				        		evidence-based medicine;
			        		
			        		
			        		
				        		expert consensus
			        		
			        		
	        			
        			
        		
 
        	
            
            	- MeSH:
            	
	        			
	        				
	        				
				        		
					        		China;
				        		
			        		
				        		
					        		Consensus;
				        		
			        		
				        		
					        		Drugs, Chinese Herbal;
				        		
			        		
				        		
					        		Female;
				        		
			        		
				        		
					        		Flavonoids;
				        		
			        		
				        		
					        		Humans;
				        		
			        		
				        		
					        		Medicine, Chinese Traditional;
				        		
			        		
				        		
					        		Pregnancy
				        		
			        		
	        			
	        			
            	
            	
 
            
            
            	- From:
	            		
	            			China Journal of Chinese Materia Medica
	            		
	            		 2020;45(10):2296-2299
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	With the advancement of the aging process, cerebrovascular disease has become China's first cause of death. Injection of Breviscapine is a type of traditional Chinese medicine injections published in the Chinese Pharmacopoeia of 2015 Edition and the National Basic Medical Insurance, Industrial Injury Insurance and Maternity Insurance Drug Catalogue, and used to treat ischemic cerebrovascular disease in clinic. In order to further improve clinicians' understanding of the drug and guidance of its rational clinical use, we gave full consideration of clinical research evidences and expert experience, followed the procedures developed based on expert consensus of Chinese Academy of Traditional Chinese Medicine, and then offered recommendations for clinical problems summarized by clinical first-line investigations and evidence-based clinical problems according to internationally accepted evidence grading and recommendation standards, i.e. Grade. As for clinical problems without evidence, we reached through nominal group method, and formed consensus recommendations. Safety issues of Injection of Breviscapine, such as indication, syndrome, dosage, course of treatment, precautions, suggestions and contraindications, were defined to improve clinical efficacy, promote rational drug use and reduce drug risks. This consensus needs to be revised in the future based on emerging clinical issues and evidence-based updates in practical applications.