Heat-Clearing Chinese Medicines in Lipopolysaccharide-Induced Inflammation.
10.1007/s11655-020-3256-7
- Author:
Zi-Bin LU
1
;
Jin-Ying OU
1
;
Hui-Hui CAO
1
;
Jun-Shan LIU
1
;
Lin-Zhong YU
2
Author Information
1. Traditional Chinese Pharmacological Laboratory, Third Level Research Laboratory of State Administration of Traditional Chinese Medicine, School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, 510515, China.
2. Traditional Chinese Pharmacological Laboratory, Third Level Research Laboratory of State Administration of Traditional Chinese Medicine, School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, 510515, China. yulzh@smu.edu.cn.
- Publication Type:Journal Article
- Keywords:
Chinese medicine;
heat-clearing;
inflammation;
lipopolysaccharide;
review
- From:
Chinese journal of integrative medicine
2020;26(7):552-559
- CountryChina
- Language:English
-
Abstract:
Lipopolysaccharide (LPS)-induced inflammation causes massive threatening diseases, such as sepsis, acute lung injury and multiple organ dysfunction syndrome. Efficient treatment to prevent inflammation is crucial in LPS-induced inflammatory diseases. Heat-clearing Chinese medicines (CMs) have been used to ameliorate LPS-induced inflammation in China for centuries. Heat-clearing CMs regulate inflammatory pathways, thereby inhibiting the release of inflammatory factors. This review aimed to introduce promising heat-clearing CMs countering LPS-induced inflammation in the last 5 years, exploring the underlying molecular mechanisms.
