Coagulation and immune function indicators for monitoring of coronavirus disease 2019 and the clinical significance.
10.11817/j.issn.1672-7347.2020.200314
- Author:
Junhua ZHANG
1
,
2
;
Tie LI
3
;
Rong HUANG
1
;
Rong GUI
1
,
4
,
5
;
Sai CHEN
1
,
6
Author Information
1. Department of Blood Transfusion, Third Xiangya Hospital, Central South University, Changsha
2. xy3zhangjunhua@csu.edu.cn.
3. Department of Laboratory Medicine, First People's Hospital of Yueyang, Yueyang Hunan 414000, China.
4. aguirong@
5. com.
6. 1754142340@qq.com.
- Publication Type:Journal Article
- Keywords:
coagulation function;
coronavirus disease 2019;
immune function;
pneumonia
- MeSH:
Aged;
Betacoronavirus;
Blood Coagulation;
China;
Coronavirus Infections;
diagnosis;
immunology;
Humans;
Immune System;
physiopathology;
Middle Aged;
Pandemics;
Pneumonia, Viral;
diagnosis;
immunology
- From:
Journal of Central South University(Medical Sciences)
2020;45(5):525-529
- CountryChina
- Language:English
-
Abstract:
OBJECTIVES:To explore the significance of coagulation and immune function indicators in clinical diagnosis and treatment of coronavirus disease 2019 (COVID-19).
METHODS:All patients with COVID-19 diagnosed and treated in First People's Hospital of Yueyang from January to March 2020 were enrolled. The general data of patients were collected. The patients were assigned into a light group (=20), an ordinary group (=33), a severe group (=23), and a critically severe group (=7) according to the severity of the disease. Coagulation and immune function indicators of each group were compared, and the relevance of coagulation and immune function indicators was analyzed.
RESULTS:The age of COVID-19 patients in Yueyang City was mainly between 45 and 65 years old. There was a significant difference in the coagulation function and immune-related indicators in each group of patients (all <0.05).
CONCLUSIONS:There are some abnormalities in coagulation and immune function in patients with COVID-19, which possess significance for clinical diagnosis and treatment of the disease.
