Clinical effect of platelet-rich fibrin combined with bone substitute in alveolar ridge preservation
	    		
	    			
	    			
		        		
			        		
		        		
			        
		   		
		   		
		   			
		   		
	    	
    	 
    	10.12016/j.issn.2096-1456.2020.06.004
   		
        
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		ZHANG Yun
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		WANG Yanmei
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		HE Jiacai
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. Dental Implant Center, Stomatologic Hospital, Anhui Medical University
			        		
		        		
	        		
        		 
        	
        	
        	
        		- Publication Type:Journal Article
 
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		extraction socket;
			        		
			        		
			        		
				        		alveolar ridge preservation;
			        		
			        		
			        		
				        		platelet-rich fibrinogen;
			        		
			        		
			        		
				        		Bio-Oss®bone substitute;
			        		
			        		
			        		
				        		early soft tissue healing;
			        		
			        		
			        		
				        		postoperative pain;
			        		
			        		
			        		
				        		alveolar bone height;
			        		
			        		
			        		
				        		alveolar bone width
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			Journal of Prevention and Treatment for Stomatological Diseases
	            		
	            		 2020;28(6):361-366
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	Objective:To study the clinical outcomes of implanting platelet rich fibrinogen (PRF) mixed with Bio-Oss® in the extraction socket for alveolar ridge preservation and to provide evidence for clinical application. 
				        	
				        
				        	Methods:Thirty-six patients who underwent alveolar ridge preservation were enrolled. Thirty-six extraction sites were divided into two groups: PRF mixed with Bio-Oss® group (test group) and Bio-Oss® alone (control group). Bone dimensional changes in height and width were measured by CBCT before and 6 months after surgery, and early soft tissue healing and postoperative pain sensation were evaluated clinically 1 week after surgery.
				        	
				        
				        	 Results : There was no significant difference in the alveolar bone height (-1.48 ± 0.40) mm between the test group and the control group. The difference in the alveolar bone width between the test group (-1.09 ± 0.42) mm and the control group (-1.35 ± 0.22) mm was statistically significant (z=-2.63, P=0.01). The postoperative pain score of the test group was 2.39 ± 1.20, and that of the control group was 3.39 ± 1.65, the difference was statistically significant (t=-2.083, P=0.045). There was no significant difference in soft tissue healing between the test group and the control group.
				        	
				        
				        	Conclusion :The use of PRF mixed with Bio-Oss ®in the alveolar ridge preservation procedure can reduce alveolar bone absorption and postoperative pain.
				        	
				        
				    
			     
	        
	        
	        	- Full text:富血小板纤维蛋白联合骨替代材料应用于牙槽嵴位点保存术的临床效果.pdf