Recent advances in the discovery and development of Ebola virus inhibitors
10.16438/j.0513-4870.2019-0859
- VernacularTitle:埃博拉病毒抑制剂研究新进展
- Author:
Yu-jie REN
1
;
Shuo ZHANG
1
;
Fen-ju WEI
1
;
Xin-yong LIU
1
;
Peng ZHAN
1
Author Information
1. Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, Jinan 250012, China
- Publication Type:Research Article
- Keywords:
Ebola virus;
filovirus;
antiviral;
inhibitor;
small molecule
- From:
Acta Pharmaceutica Sinica
2020;55(4):694-702
- CountryChina
- Language:Chinese
-
Abstract:
Ebola virus is extremely virulent and highly contagious. Ebola virus causes outbreaks of severe hemorrhagic fever, with human mortality rates of up to 90%. There is currently no preventive or therapeutic treatment in the form of vaccines, biological or small molecular agents. Currently, a lot of anti-Ebola virus agents have been reported. Here, we review the latest advances in this field.
