Role of microRNA in hepatitis B virus infection-related diseases
10.3969/j.issn.1001-5256.2020.03.041
- VernacularTitle:microRNA在HBV感染相关疾病中的作用
- Author:
Lili LIU
1
;
Heling SU
;
Yongming LIU
Author Information
1. Department of Biochemistry and Molecular Biology, Guilin Medical University, Guilin, Guangxi 541004, China
- Publication Type:Research Article
- Keywords:
liver diseases;
microRNAs;
hepatitis B virus
- From:
Journal of Clinical Hepatology
2020;36(3):662-665
- CountryChina
- Language:Chinese
-
Abstract:
MicroRNA (miRNA) plays an important role in viral diseases by regulating post-transcriptional gene expression. MiRNA can affect the replication and gene expression of hepatitis B virus (HBV) in host cells, while HBV can regulate the expression of host miRNA to provide a favorable environment for its own survival and replication. This miRNA-mediated relationship between HBV and host is an important basis for the pathogenesis of HBV infection-related diseases. This article reviews the research advances in the role of miRNA in HBV infection-related chronic hepatitis B, liver cirrhosis, and hepatocellular carcinoma.
