Investigation and Study on Occupational Exposure for Hazardous Drugs of Healthcare Workers in Shaanxi Province and Relative Cognition Level
	    		
		   		
	    	
    	
    	
   		
        
        	
        		- VernacularTitle:陕西省医护人员的危害药品职业暴露及相关认知水平调查研究
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Yurong ZHU
			        		
			        		
			        		
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			        		Xin LONG
			        		
			        		
			        		
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			        		Zheng WANG
			        		
			        		
			        		
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			        		Kai CHENG
			        		
			        		
			        		
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			        		Yanshen CHEN
			        		
			        		
			        		
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			        		Hua LIU
			        		
			        		
			        		
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			        		Weiyi FENG
			        		
			        		
			        		
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			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. Dept. of Pharmacy,the First Affiliated Hospital of Xi’an Jiaotong University,Xi’an 710061,China
			        		
		        		
	        		
        		 
        	
        	
        	
        		- Publication Type:Journal Article
 
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Hazardous drugs;
			        		
			        		
			        		
				        		Chemotherapy drug
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			China Pharmacy
	            		
	            		 2020;31(7):869-872
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
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		        	Abstract:
			       	
			       		
				        
				        	OBJECTIVE:To understand the situation of healthcar e workers’occupational exposure of hazardous drugs (chemotherapeutic drugs and antiviral drug )and relative cognition level ,and to provide reference for improving the level of occupational protection. METHODS :During Oct. 2018 to Mar. 2019,healthcare workers from 12 hospitals of different levels and different departments in Shaanxi province were selected as respondents to conduct a self-designed questionnaire survey. Information we surveyed contained baseline characteristics ,hazardous drugs exposure ,physical health status ,and occupational protection. Valid questionnaires were collected and analyzed statistically. RESULTS :A totally of 1 848 questionnaires were sent out ,and 1 767 questionnaires were collected ,including 95 were pharmacists ,100 were physicians ,and 1 572 were nurses. The frequency of diarrhea and menstrual disorders in healthcare workers with long-term exposure to antiviral drugs (antiviral drug exposure group ) and cross-exposure to antiviral drugs and chemotherapeutic drugs (cross-exposure group )were significantly higher than unexposed group (P<0.05). The incidence of routine blood abnormalities in cross-exposure group ,antiviral drug exposure group and healthcare workers with long-term exposure to chemotherapy drugs (chemotherapy drug exposure group ) was higher than unexposed group by 9.13%,5.50% and 12.34%,respectively. 84.7% of the respondents had little knowledge of hazardous drugs , and 8.15% of the respondents had never received occupational protection training. Additionally ,the ratio of healthcare workers receiving occupational protection training in the cross-exposure group was significantly higher than unexposed group (P<0.05), and the ratio of healthcare workers receiving occupational protection training in antiviral drug exposure group were significantly lower than unexposed group (P<0.05). CONCLUSIONS :Long-term exposure to hazardous drugs will cause certain occupational hazards to healthcare workers. It is necessary to improve healthcare workers ’awareness of self-protection ,increase the input of hospitals in occupational protection training and establish occupational protection standards in order to improve the current situation of occupational protection of healthcare workers.