Clinical value of transient elastography (FibroScan) in detection of clonorchiasis
10.16250/j.32.1374.2019004
- VernacularTitle:瞬时弹性成像探测仪FibroScan在华支睾吸虫病中的临床应用
- Author:
Bin ZHONG
1
;
Jian-Lin WU
1
;
Xiao-Lin WAN
2
;
Guo-Li LÜ
2
;
Wen-Qian TANG
2
;
Zhi-Hua JIANG
2
Author Information
1. Guangxi Medical University, Nanning 530023, China
2. Guangxi Zhuang Autonomous Region Center for Disease Control and Prevention, China
- Publication Type:Journal Article
- Keywords:
Clonorchiasis;
Transient elastography;
Liver stiffness;
Therapeutic efficacy assessment
- From:
Chinese Journal of Schistosomiasis Control
2019;31(3):319-322
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assess the clinical significance of transient elastography (Fibroscan) in detection of clonorchiasis, so as to provide new insights into the assessment of therapeutic efficacy of deworming. Methods The liver stiffness measurement (LSM) values were measured in parasitologically diagnosed clonorchiasis patients using FibroScan before and after deworming, and the patients’age, gender, body mass index (BMI), duration of raw fish consumption and total amount of raw fish consumption were collected for correlation analyses. Results The clonorchiasis patients’age, gender, BMI, duration of raw fish consumption and total amount of raw fish consumption had no associations with pre-treatment LSM values (r/rs = 0.189, 0.073, 0.180; 0.071, –0.098, 0.033; 0.166, 0.309, 0.172; 0.235, 0.247, 0.209; 0.164, 0.277, 0.088; all P values > 0.05). There was a significant difference in the LSM values from the seventh, eighth and ninth intercostal space prior to deworming (F = 3.259, P < 0.05), and no significant difference was detected after deworming (F = 0.851, P > 0.05). The LSM values from the seventh, eighth and ninth intercostal space were significantly lower pre-deworming than post-deworming (t = 6.724, 5.603, 2.884; all P values < 0.05). Conclusion FibroScan is feasible to assess the therapuetic efficacy of deworming in patients with clonorchiasis; however, measurement at various sites affects the LSM value.
