Application of metabolomics in screening potential biomarkers for kidney transplantation

VernacularTitle: 代谢组学在筛选肾移植潜在生物标志物中的应用
Author: Chi-yu MA ¹ ; Wen XUE ² ; Dong-e TANG ³ ; Yong DAI ³
Author Information

1. College of LifeScience,Guangxi Normal University,Guilin 541006,Guangxi,China
2. PLA Key Laboratory of Metabolic Disease of Guangxi,PLA 924st Hospital,Guilin 541002,Guangxi,China
3. The Second Clinical Medical College of Jinan University,Clinical Medicine Research Center of Shenzhen People's Hospital,Shenzhen 518020,Guangdong,China
Publication Type:Journal Article
Keywords: kidney transplantation; metabolomics; biomarkers
From: Journal of Medical Postgraduates 2020;33(3):333-336
CountryChina
Language:Chinese
Abstract: Metabolomics, which inherits the ideas of genomics and proteomics, has been widely applied in clinical medical research. In the field of kidney transplantation, changes, which occur in the concentration of small molecule metabolites in blood or urine, can be used to identify organs at risk of acute rejection, locate organ damage, and monitor graft function. This article reviews the problems in the field of kidney transplantation, the concepts, characteristics and research methods of metabolomics, as well as the progress in the application of kidney transplantation and the biomarkers that have been discovered.