The progression of intervention cell death in kidney diseases
10.16571/j.cnki.1008-8199.2019.08.018
- VernacularTitle: 干预细胞死亡在肾脏病治疗中的研究进展
- Author:
Xiong TANG
1
;
Jiong ZHANG
1
;
Jin-quan WANG
1
Author Information
1. National Clinical Research Center of Kidney Diseases, Jinling Hospital, Nanjing University School of Medicine, General Hospital of Eastern Theater Command, PLA, Nanjing 210002, Jiangsu,China
- Publication Type:Journal Article
- Keywords:
apoptosis;
chronic kidney disease;
acute kidney injury;
homeostasis
- From:
Journal of Medical Postgraduates
2019;32(8):877-881
- CountryChina
- Language:Chinese
-
Abstract:
Precise regulation of cell death and survival is essential for proper maintenance of organismal homeostasis, development, and immune system. Kidney diseases, especially acute histology changings linked ischemia-reperfusion injury, are among illnesses that are profoundly affected by improper regulation or execution of cell death pathways. Given the truth that improper regulation of cell death participates in a common pathway of various pathologies, specific therapeutic strategies that aim at the regulation are promising. In current review, we reviewed the most common pathway on cell death in renal injury, also described several potential therapy strategies that may influence the prognosis of kidney diseases，such as targeting receptor interacting protein 1 kinase.
