Maspin in tumor formation and progression
10.16571/j.cnki.1008-8199.2019.07.016
- VernacularTitle: Maspin 在肿瘤发生发展中的作用
- Author:
Qian SUN
1
;
Huan LI
1
;
Long-bang CHEN
1
Author Information
1. Department of Oncology, Jinling Hospital, Medical School of Nanjing University/General Hospital of Eastern Theater Command, PLA, Nanjing 210002, Jiangsu, China
- Publication Type:Journal Article
- Keywords:
mammary serine protease inhibitor;
structure and distribution;
tumor inhibition
- From:
Journal of Medical Postgraduates
2019;32(7):750-754
- CountryChina
- Language:Chinese
-
Abstract:
Maspin gene is a tumor suppressor that encodes serine protease inhibitor. It was found that maspin could induce apoptosis, inhibit the invasion and metastasis of tumor cells, and suppress angiogenesis. In recent years, maspin has also been found to be associated with host immunity. The review is to summarize structure distribution, tumor inhibition mechanism and immunological correlation of maspin.
