Study on the effect of vaginal lavage with ozonated water on normal vaginal microecology and lactobacilli

Qiong-qiong ZHANG; Ying LIU; Lei ZHANG; Rui CHEN; Zhi TAO; Zhen-yu HUANG; Tao LYU; Qin-ping LIAO

Return

Study on the effect of vaginal lavage with ozonated water on normal vaginal microecology and lactobacilli

Author: Qiong-qiong ZHANG ¹ ; Ying LIU ¹ ; Lei ZHANG ¹ ; Rui CHEN ¹ ; Zhi TAO ¹ ; Zhen-yu HUANG ¹ ; Tao LYU ¹ ; Qin-ping LIAO ¹
Author Information

1. Department of Obstetrics and Gynecology,Beijing Tsinghua Changgung Hospital,School of Clinical Medicine,Tsinghua University Beijing 102218,China
Publication Type:Journal Article
Keywords: ozonated water; vaginal lavage; vaginal microecology; lactobacillus; high-throughput sequencing
From: Chinese Journal of Practical Gynecology and Obstetrics 2019;35(04):450-454
CountryChina
Language:Chinese
Abstract: OBJECTIVE: To explore the changes of normal vaginal micro-ecological environment after vaginal lavage with ozonated water and its effect on lactobacillus.METHODS: From April to October 2016,30 volunteers with normal vaginal microecological examination results were recruited from female workers in Beijing Tsinghua Changgung Hospital and selected to receive vaginal lavage with ozonated water,during non-menstrual periods 5 minutes per day,for 3 consecutive days.The vaginal secretions were taken before the first vaginal ozone lavage,the first week,the second week and the third week after the last lavage,and the microecological examination and the difference in the diversity and abundance of the vaginal microbial community were analyzed after 16 S rRNA high-through put sequencing.RESULTS: Before and after healthy women received ozone water for vaginal lavage,there were no significant differences in the microflora evaluation of vaginal secretions,vaginal microbial community diversity or lactobacillus(|cor. p| <0.2).CONCLUSION: Ozonated water for vaginal lavage does not destroy the normal vaginal microecology and has no significant effect on lactobacilli.