Risk factors of venous thromboembolism and evaluation of existing risk assessment models for predicting venous thromboembolism in medical oncology inpatients
- Author:
Xue-qian MEN
1
;
He-ming LI
;
Qian DONG
1
;
Yuan-he WANG
1
;
Jin ZHOU
1
;
Yan-rong LI
1
;
Jing-dong ZHANG
1
Author Information
- Publication Type:Journal Article
- Keywords: cancer; venous thromboembolism; risk factors; risk assessment model
- From: Chinese Journal of Practical Internal Medicine 2019;39(08):694-697
- CountryChina
- Language:Chinese
- Abstract: OBJECTIVE: To investigate the risk factors of venous thrombosis(VTE) and to evaluate the predictive ability of the existing risk assessment models(RAM) in medical oncology inpatients. METHODS: In this study, 252 medical oncology inpatients were divided into study group(63) and control group(189) according to VTE. Logistic regression analysis was performed to identify the risk factors of VTE and to evaluate the predictive ability of KRS and PPS. RESULTS: This study showed that previous VTE, staying in bed≥3 d,platelet count≥350×10~9/L, D-dimer>0.55 mg/L and stage IV cancer were associated with VTE risks(OR=12.149, 3.672, 3.144, 5.263,1.439, 1.382, P<0.05). Furthermore, we performed the risk assessment of VTE according to KRS and PPS respectively. For KRS, in the low-and intermediate-risk subgroup, statistical difference existed between study and control group(P<0.01); but in high-risk subgroup,no significant difference existed between study and control group. For PPS, no significant difference existed between study and control group. CONCLUSION: For the inpatients of medical oncology department, previous VTE, staying in bed≥3 d, platelet count≥350×10~9/L, D-dimer>0.55 mg/L, and stage IV cancer are independent risk factors of VTE. Compared with the limited predictive ability of PPS,KRS can predict VTE very well for low-and intermediate-risk patients.
