Changes of color pattern reversal visual evoked potential of primary glaucoma.
- Author:
Ping-Bao WANG
1
;
Yang TONG
;
Zhao-Hua XIA
;
Qian TAN
;
Xiao-Bo XIA
Author Information
1. Department of Ophthalmology, Xiangya Hospital, Central South University, Changsha 410008, China. pingbao-wang@hotmail.com
- Publication Type:Journal Article
- MeSH:
Adult;
Aged;
Color Perception;
physiology;
Color Perception Tests;
methods;
Evoked Potentials, Visual;
physiology;
Female;
Glaucoma;
diagnosis;
physiopathology;
Humans;
Male;
Middle Aged
- From:
Journal of Central South University(Medical Sciences)
2008;33(9):821-825
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate the changes of color pattern reversal visual evoked potential (CPR-VEP)of primary glaucoma using different temporal frequencies, and to search for the best temporal frequency parameters and color parameters.
METHODS:Vision Monitor visual electrophysiograph (Métrovision, France) was used to record CPR-VEP at different temporal frequencies (1, 2, 4, 8, 16, and 32 Hz) and different color stimulations (black/white, red/green, blue/yellow) in 41 cases (70 eyes) with primary glaucoma (glaucoma group) and 13 normal subjects (26 eyes) (normal control group). P100 wave amplitudes were compared.
RESULTS:(1) In the normal control group, P100 amplitudes declined while the temporal frequency of black/white stimulation was increasing, but they had peaks at 2 Hz and 8 Hz red/green stimulation and blue/yellow stimulation. (2) In the glaucoma group, CPR-VEP P100 declined while temporal frequency was increasing under 3 color stimulations, but had a peak at 8 Hz. At 2 Hz-16 Hz, P100 amplitudes were related with the mean defect of Humphrey visual field, especially with all 3 color stimulations at 8 Hz and with blue/yellow stimulation at 2 Hz and 16 Hz. (3) P100 amplitude was most different under the 3 color stimulations between the 2 groups at 8 Hz.
CONCLUSION:The changes of CPR-VEP P(100) amplitude can objectively reflect the glaucoma visual function damage. CPR-VEP P100 amplitude has certain value in studying glaucoma under different color stimulations (black/white, red/green, blue/yellow) at 8 Hz, and blue/yellow stimulation at 2 Hz and 16 Hz.
