Heteroclitins R-S: new dibenzocylooctadiene lignans from Kadsura heteroclita.
10.1016/S1875-5364(14)60105-9
- Author:
Min CHEN
1
;
You-Ping LUO
2
;
Yan-Lin ZOU
3
;
Ling-Hu LANG
3
;
Dao-Feng CHEN
4
Author Information
1. Key Laboratory on Luminescence and Real-Time Analysis (Ministry of Education), College of Pharmaceutical Sciences, Southwest University, Chongqing 400715, China. Electronic address: mminchen@swu.edu.cn.
2. Key Laboratory on Luminescence and Real-Time Analysis (Ministry of Education), College of Pharmaceutical Sciences, Southwest University, Chongqing 400715, China; College of Chemistry and Chemical Engineering, HaiNan Normal University, Hai Kou 571158, China.
3. Key Laboratory on Luminescence and Real-Time Analysis (Ministry of Education), College of Pharmaceutical Sciences, Southwest University, Chongqing 400715, China.
4. Department of Pharmacognosy, School of Pharmacy, Fudan University, Shanghai 201203, China.
- Publication Type:Journal Article
- Keywords:
Dibenzocylooctadiene Lignan;
Heteroclitins R-S;
Kadsura heteroclita;
Schisandraceae
- MeSH:
Kadsura;
chemistry;
Lignans;
chemistry;
isolation & purification;
Molecular Structure;
Plant Extracts;
chemistry
- From:
Chinese Journal of Natural Medicines (English Ed.)
2014;12(9):689-692
- CountryChina
- Language:English
-
Abstract:
AIM:To study the dibenzocylooctadiene lignans from the stems of Kadsura heteroclita.
METHOD:Chromatographic separations of silica gel and semi-preparative HPLC were used. All of the structures were elucidated on the basis of spectroscopic analysis, including 2D-NMR and HR-MS techniques.
RESULTS:Four dibenzocylooctadiene lignans were isolated from K. heteroclita. Their structures were identified as heteroclitin R (1), heteroclitin S (2), gonisin O (3), and schisanlignone A (4).
CONCLUSION:Heteroclitin R (1) and heteroclitin S (2) are new natural lignans.
