Advances of the traditional Chinese medicines modulating endoplasmic reticulum stress
10.11665/j.issn.1000-5048.20150401
- VernacularTitle:中药调节内质网应激的研究进展
- Author:
Huana ZHOU
1
;
Nan JIANG
;
Yuwei HAN
;
Junping KOU
Author Information
1. 江苏省中药评价与转化重点实验室，中国药科大学中药复方研究室
- Publication Type:Journal Article
- Keywords:
endoplasmic reticulum stress;
traditional Chinese medicine;
tumor;
cardiovascular disease;
neurological disorder;
diabetes
- From:
Journal of China Pharmaceutical University
2015;46(4):385-392
- CountryChina
- Language:Chinese
-
Abstract:
The endoplasmic reticulum is an important organelle for eukaryotic cell protein synthesis, folding and secretion. Perturbation of endoplasmic reticulum homeostasis causes endoplasmic reticulum stress. It has been considered as one of important ways and new strategies to regulate endoplasmic reticulum stress in the treatment of multiple diseases. This paper mainly reviews the advances in the research on traditional Chinese medicines for modulating endoplasmic reticulum stress related to cancer, cardiovascular diseases, neurological diseases, diabetes and other complex diseases in recent years, aiming to provide some clues and references for exploring the characteristics and possible mechanism of traditional Chinese medicines treating related diseases.
