Advances in the research of cytokine storm mechanism induced by Corona Virus Disease 2019 and the corresponding immunotherapies
10.3760/cma.j.cn501120-20200224-00088
- VernacularTitle: 新型冠状病毒肺炎引发细胞因子风暴的机制及相关免疫治疗研究进展
- Author:
Cheng CHEN
1
;
Xiaorong ZHANG
1
;
Zhenyu JU
2
;
Weifeng HE
1
Author Information
1. State Key Laboratory of Trauma, Burns, and Combined Injury, Institute of Burn Research, the First Affiliated Hospital of Army Medical University (the Third Military Medical University), Chongqing Key Laboratory for Disease Proteomics, Chongqing 400038, China
2. Institute of Aging and Regenerative Medicine, Jinan University, Guangzhou 510632, China
- Publication Type:Journal Article
- Keywords:
Cytokines;
Immune system;
Corona Virus Disease 2019;
Cytokine storm;
Immunotherapy
- From:
Chinese Journal of Burns
2020;36(0):E005-E005
- CountryChina
- Language:Chinese
-
Abstract:
Corona Virus Disease 2019 (COVID-19) has seriously affected the treatment of patients and social stability. In the later stage of disease, some COVID-19 patients may develop into acute respiratory distress syndrome or even multiple organ failure. However, one of the most important mechanism underlying the deterioration of disease is cytokine storm. At present, some therapies such as interleukin-6 antibody blocker, stem cell therapy, and transfusion of convalescent plasma have been applied to counteract the cytokine storm and have made some progress. This article reviews the influences of cytokine storm syndrome on the COVID-19 and the corresponding immunotherapies to resist cytokine storm.
