Advances in the diagnostic pathological features of precancerous lesions of hepatocellular carcinoma 
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3760/cma.j.issn.1007-3418.2019.07.004
   		
        
        	
        		- VernacularTitle: 肝细胞癌癌前病变病理诊断特征的研究进展 
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Yanqing ZHAO
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Wenming CONG
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. Department of Pathology, Shanghai Eastern Hepatobiliary Surgery Hospital, Shanghai 200438, China
			        		
		        		
	        		
        		 
        	
        	
        	
        		- Publication Type:Journal Article
 
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Carcinoma, hepatocellular;
			        		
			        		
			        		
				        		Precancerous lesions;
			        		
			        		
			        		
				        		Dysplastic nodule;
			        		
			        		
			        		
				        		Pathology
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			Chinese Journal of Hepatology
	            		
	            		 2019;27(7):491-493
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	 The occurrence of hepatocellular carcinoma (HCC) is a multistep development process through precancerous lesions. A precancerous lesion of HCC is classified into hepatocyte dysplasia at the cytological level and dysplastic nodules at the histological level, and the corresponding lesion subtypes have different risks of canceration. Pathology is the "gold standard" for the diagnosis of early stage HCC and its precancerous lesions. However, it also faces many difficulties and challenges, such as the accumulation of experience in the pathological diagnosis, the understanding and grasp of key points of histopathological diagnosis and differential diagnosis, the combination application of immune and molecular diagnostic markers, and many others. This article briefly discusses the key points of pathological features and differential diagnosis of precancerous lesions of HCC.