Laryngopharyngeal reflux disease and laryngeal precancerous lesions 
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3760/cma.j.issn.1673-0860.2017.08.021
   		
        
        	
        		- VernacularTitle: 咽喉反流和喉癌前病变 
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Zhenwei LI
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Shuihong ZHOU
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310003, China
			        		
		        		
	        		
        		 
        	
        	
        	
        		- Publication Type:Review
 
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Gastroesophageal reflux;
			        		
			        		
			        		
				        		Pharyngeal dieases;
			        		
			        		
			        		
				        		Laryngeal dieases;
			        		
			        		
			        		
				        		Precancerous conditions
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			Chinese Journal of Otorhinolaryngology Head and Neck Surgery
	            		
	            		 2017;52(8):637-639
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	 The laryngopharyngeal reflux disease (LPRD) is a general term for a series of symptoms and signs caused by reflux of the stomach contents to the upper part of the esophageal sphincter. In recent years, the laryngopharyngeal reflux (LPR) is getting more and more attention as laryngeal precancerous lesions and risk factors of laryngeal cancer. Laryngeal precancerous lesions plays a important role in the development of laryngeal cancer process. This article will review the role and mechanisms of LPR in the laryngeal precancerous lesions, and the status of anti-reflux in the treatment of laryngeal precancerous lesions.