A meta-analysis of Yupingfeng powder in conjunction of western medicine on cough variant asthma
10.3760/cma.j.issn.1673-4246.2018.08.010
- VernacularTitle: 玉屏风散联合西药治疗咳嗽变异性哮喘随机对照试验的meta分析
- Author:
Wei GAO
1
;
Lirong MA
;
Minhua CHEN
;
Yu LI
;
Fang SU
Author Information
1. Department of Respiratory Medicine, Chaoyang District Traditional Chinese Medicine Hospital of Beijing, Beijing 100020, China
- Publication Type:Journal Article
- Keywords:
Yu Ping Feng San;
Cough variant asthma;
Randomized controlled trial;
Meta-analysis
- From:
International Journal of Traditional Chinese Medicine
2018;40(8):722-726
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the efficacy and safety of Yupingfeng powder in conjunction treatment of western medicine on cough variant asthma (CVA).
Methods:We searched CNKI, Wanfang database, VIP database and PubMed through computer from the database building to October 31st 2017. The randomized controlled trails (RCT) with the comparison in the treatment of CVA with Yupingfeng powder and western medicinal were identified and included. The quality of RCTs was assessed by Jadad scores, and meta-analyses were performed by Review Manager 5.3 software.
Results:Totally 15 RCTs involving 1 318 patients were included into the study, which all belonged to the low methodological quality. The meta-analysis results showed that compared with the western medicine alone, the treatment in conjunction of Yupingfeng powder can significantly improve the clinical effective rate [OR=3.45, 95% CI (2.38-5.02), P<0.01], reduce the recurrence rate [OR=0.25, 95% CI (0.16-0.38), P<0.01]. There were no statistical significant differences with untoward effect between above two treatment groups [OR=0.70, 95% CI (0.34-1.46), P=0.35].
Conclusions:The Yupingfeng powder combined with the routine therapy may improve the clinical effective rate, and reduce the recurrence rate for CVA patients. However, we need more high-quality RCTs to comfirm such results.
