Determination of p-Anisidine in workplace air by HPLC
10.3760/cma.j.issn.1001-9391.2018.06.023
- VernacularTitle: 工作场所空气中对氨基苯甲醚检测的高效液相色谱法
- Author:
Kaiyou JIANG
1
;
Wenhua QIN
;
Qi GEN
;
Chengming MENG
;
Shanfa YU
Author Information
1. Henan Provincial Institute of Occupational Health, Zhengzhou 450052, China
- Publication Type:Journal Article
- Keywords:
chromatography;
High performance liquid;
Workplace;
P-Anisidine
- From:
Chinese Journal of Industrial Hygiene and Occupational Diseases
2018;36(6):468-471
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To establish an HPLC method for determining p-Anisidine in workplace air.
Methods:An C18 capillary column was used with the detection wavelength of 240 nm, the methanol solution (v/v=62:38) as mobile phase, the flow rate was 0.9 ml/min, and the injection volume was 20 μl.
Results:The linear range (μg/ml) for p-Anisidine was 0~100; correlation coefficient was 0.999 7; the detection limit was 0.15 μg/ml; the average precision of RSD was 4.4%. The sampling efficiency was more than 95% using silicone tube as sampling filter. Sample can be stored at room temperature for more than 7 d.
Conclusion:the method appered to be accurate, simple, sensitive and reliable, also have a high sampling efficiency, and can be usd to determine p-anisidine in workplace air simultaneously.
