Correlation between FibroScan, APRI Detecting the degree of esophageal and gastric varices of liver cirrhosis
10.3760/cma.j.issn.1007-3418.2018.05.006
- VernacularTitle: FibroScan和APRI对肝硬化食管胃底静脉曲张程度的预测价值
- Author:
Shuai WANG
1
;
Wei ZHANG
1
;
Fan ZHANG
1
;
Zhen QIAN
2
;
Lifeng WANG
1
;
Lejie REN
1
;
Song YANG
1
Author Information
1. Department of Gastroenterology, the Third Affiliated Hospital of Henan University of Science and Technology, Luoyang 471003, China
2. The First Affiliated Hospital of Henan University of Science and Technology, Luoyang 471003, China
- Publication Type:Journal Article
- Keywords:
Liver cirrhosis;
Esophagus;
Varicose veins;
Diagnosis;
FibroScan;
APRI
- From:
Chinese Journal of Hepatology
2018;26(5):342-346
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the predictive value of transient elastography (FibroScan), aspartate aminotransferase-to-platelet ratio index (APRI) in the detection of esophagogastric varices in patients with liver cirrhosis.
Methods:236 patients with liver cirrhosis who met the criteria were selected. All patients underwent gastroscopy. According to the degree of esophagogastric varices, patients were divided into four groups: none, mild, moderate, and severe. The patient's liver stiffness (LSM) and aspartate aminotransferase- to-platelet ratio index (APRI) were measured within 3 days of gastroscopy. One-way analysis of variance was used to compare multi-group data. The ROC curves of LSM, APRI, LSM+APRI in patients with liver cirrhosis with esophageal varices were plotted and their area under the ROC curve (AUC) were compared.
Results:The area under the ROC curve of LSM, APRI, LSM + APRI in patients with mild esophagogastric varices were 0.856, 0.900, and 0.906, respectively; moderate esophagogastric varices were 0.857, 0.924, and 0.923 respectively; and severe esophagogastric varices were 0.801, 0.903, and 0.901, respectively.
Conclusion:APRI and LSM+APRI have better predictive value for patients with cirrhosis who have esophagogastric varices.
