Advances in tracheal transplantation
10.3760/cma.j.issn.1673-0860.2018.01.019
- VernacularTitle: 气管移植研究进展
- Author:
Pengcheng CUI
1
Author Information
1. Department of Otorhinolaryngology Head and Neck Surgery, Tangdu Hospital, Fourth Military Medical University, Xi′an 710038, China
- Publication Type:Review
- Keywords:
Trachea;
Transplantation, homologous;
Neovascularization, physiologic;
Immunosuppression
- From:
Chinese Journal of Otorhinolaryngology Head and Neck Surgery
2018;53(1):73-75
- CountryChina
- Language:Chinese
-
Abstract:
The length of tracheal defect or stenosis exceeded 5 cm could not be treated by simple resection and end-to-end anastomosis of the remaining trachea. Various ways of tracheal replacement had appeared sequentially, such as radial forearm free flap with cartilage grafts, tracheal tissue-engineering and tracheal allotransplantation. Among these methods, tracheal allotransplantation displayed a better long-term result. In this review, we are focused on recent advances in tracheal allotransplantation, particularly on revascularization and reepithelialization of graft, as well as on the application of immunosuppressive agents.
