Recurrence pattern and influencing factors of intensity-modulated radiotherapy for cervical cancer
10.3760/cma.j.issn.0253-3766.2019.08.003
- VernacularTitle: 宫颈癌根治调强放疗的复发模式及影响因素
- Author:
Feng ZHANG
1
;
Xiaomeng DU
2
;
Manni HUANG
1
Author Information
1. Department of Gynecologic Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China
2. Department of Gynecologic Oncology, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing 100006, China
- Publication Type:Review
- Keywords:
Cervical neoplasms;
Intensity modulated radiation therapy;
Brachytherapy;
Recurrence mode
- From:
Chinese Journal of Oncology
2019;41(8):569-572
- CountryChina
- Language:Chinese
-
Abstract:
With the rapid development of precise radiotherapy technology, the use of intensity-modulated radiation therapy (IMRT) in gynecological malignant tumor has been gradually increased. IMRT could result in a good local control rate as well as superior clinical outcome in patients with cervical cancer after radical radiotherapy. The recurrence pattern of radiotherapy includes in-field recurrence, out-of-field and combined failure. The recurrence pattern of radical IMRT for cervical cancer is mainly out-of-field recurrence. Out-of-field recurrence may be related to inadequate imaging evaluation before treatment. In-field recurrence may be related to insufficient radiation dose in target area and differences of tumor sensitivity.
