Clinicopathological analysis on invasive micropapillary carcinoma of the breast: 16 cases
10.3760/cma.j.issn.1674-6090.2019.06.013
- VernacularTitle: 乳腺浸润性微乳头状癌16例临床病理分析
- Author:
Xiaowei ZHANG
1
;
Aijiao WU
;
Yan CHEN
;
Bifei HUANG
Author Information
1. Department of Pathology, Dongyang People’s Hospital of Zheijiang Province, Dongyang 322100, China
- Publication Type:Journal Article
- Keywords:
Breast;
Micropapillary carcinoma
- From:
Chinese Journal of Endocrine Surgery
2019;13(6):500-504
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the clinicopathological features of breast invasive micropapillary carcinoma and its treatment and prognosis.
Methods:Clinical data, radiological examination, histopathology, immunohistochemistry, therapeutic regimen and follow-up results of 16 cases of invasive micropapillary carcinoma of the breast were collected. The clinicopathological features, immunophenotype, imaging findings, treatment and prognosis were retrospectively analyzed.
Results:All the 16 cases were female, with mean age of 56.3 years (40 to 89 years) . Of the 16 patients, 4 cases were pure invasive micropapillary carcinoma, and 12 cases were mixed invasive micropapillary carcinoma. Among the 12 cases of mixed invasive micropapillary carcinoma, 1 case was mixed with invasive ductal carcinoma, mucinous carcinoma and invasive micropapillary carcinoma, and the remaining 11 cases were all non-specific invasive ductal carcinoma with invasive micropapillary carcinoma. Out of the 16 cases, 13 (81.25%) were invasive micropapillary carcinoma with axillary lymph node metastasis, axillary lymph node metastasis which was more than 4 had 7 cases (43.75%) , clinical stage Ⅲ had 8 cases (50%) . According to the pathological results, 16 cases were treated with individualized comprehensive treatment. Of the 16 patients, 14 were followed up and 2 were lost.
Conclusion:Breast infiltrating micropapillary carcinoma is a rare type of breast cancer, with high rate of axillary lymph nodes metastasis, aggressive lymphatic invasiveness, high malignancy degree and poor prognosis.
