Clinical Efficiency of Modified Erchentang on Children Bronchiolitis
10.13422/j.cnki.syfjx.20191226
- VernacularTitle: 二陈汤加减治疗小儿毛细支气管炎临床疗效观察
- Author:
Ruo-gu YU
1
;
Yan-yan WU
1
;
Xiao-juan ZHANG
1
;
Chong-hui DAN
2
Author Information
1. Chongqing Health Center for Women and Children, Chongqing 400021, China
2. Chongqing Emergency Medical Center, Chongqing 400000, China
- Publication Type:Research Article
- Keywords:
modified Erchentang;
bronchiolitis;
cough;
sputum;
pulmonary function
- From:
Chinese Journal of Experimental Traditional Medical Formulae
2019;25(19):62-67
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe the clinical efficacy and safety of modified Erchentang (Juhong Tanke liquid) on children bronchitis with syndrome of sputum, cough, dys-expectoration, wheezing and pulmonary function. Method:A total of 200 children patients aged below 24 months were randomly divided into control group and observation group by random number table, with 100 cases in each group. Children in each group received basic clinical treatment, while children in treatment group was also given modified Erchentang (Juhong Tanke liquid), 2-5 mL each time, 3 times a day. Both groups were treated for 15 days. Clinical respiratory tract symptom and sign scores, cough, sputum, dys-expectoration and wheezing were evaluated and compared. Pulmonary function was detected before and after treatment for 15 days. Analysis parameters were respiratory rate (RR), tidal volume per kilogram (VT/kg), inspiratory/expiratory (TI/TE), peak time of expiratory flow (TPTEF), time to peak ratio (TPTEF/TE), peak expiratory flow (PEF), volume in peak time of expiratory flow (VPTEF), volume ratio in peak flow (PFV), terminal flows per peak expiratory flow (25/PF), rate of mid-expiratory to mid-inspiratory flow (ME/MI), respiratory resistance (Rrs), functional residual capacity per kilogram (FRC/kg) and compliance per kilogram (Crs/kg). Result:After treatment for 5 days, both groups have obviously alleviation in sputum, cough, dys-expectoration wheezing and airway function. After treatment for 5 days, sputum, cough, dys-expiratory and wheezing in treatment group were all alleviated comparing with those of control group (P<0.05). What's more, treatment group had significantly short durations in cough and wheezing. Obvious alleviations were observed in pulmonary function, PFV, 25/PF, ME/MI, Crs/kg, Rrs, FRC/kg in treatment group after treatment for 15 days, with significant differences. Conclusion:Modified Erchentang (Juhong Tanke liquid) has shown marked efficacy in children bronchitis to alleviate clinical symptoms and improve pulmonary function, with no adverse reaction, and thus is worth further promotion and application in clinic.
