Optimization of Electromagnetic Cracking Extraction Technology of Baicalin in Scutellariae Radix by Response Surface Methodology
10.13422/j.cnki.syfjx.20191349
- VernacularTitle: 响应面法优化黄芩中黄芩苷的电磁裂解提取工艺
- Author:
Ren-guang WANG
1
;
Ai-ling JIA
1
;
Zhi-dong QIU
1
;
Jing-yao YANG
1
;
Xin-shu ZHANG
1
;
Ji-qi YANG
1
Author Information
1. Key Laboratory of Active Ingredients in Traditional Chinese Medicine(TCM) Co-constructed by Jilin Province and Ministry of Education, Changchun University of Chinese Medicine, Changchun 130117, China
- Publication Type:Research Article
- Keywords:
Scutellariae Radix;
electromagnetic cracking method;
response surface methodology;
baicalin;
extraction technology;
scanning electron microscope;
material size
- From:
Chinese Journal of Experimental Traditional Medical Formulae
2019;25(21):106-111
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To optimize the extraction conditions of baicalin from Scutellariae Radix by electromagnetic pyrolysis. Method: Based on single factor experiments, taking extraction time, material size and liquid-material ratio as factors, yield of baicalin as index, extraction parameters were optimized by response surface methodology, and compared with ultrasonic method, ethanol refluxing method and decoction method. Result: The optimal extraction conditions were as follows:extraction time of 2.41 min, material size of 100 mesh, liquid-material ratio of 33 mL·g-1. Under these conditions, the yield of baicalin was 12.21%. The yields of baicalin by ethanol refluxing method, decoction method and ultrasonic method were 12.91%, 12.62% and 11.61%, respectively. The yield of baicalin by electromagnetic cracking extraction was close to several other conventional extraction methods, and the extraction time was significantly shortened. Conclusion: As a novel extraction technology of traditional Chinese medicine, electromagnetic cracking extraction has the advantages of high efficiency, energy and time saving, green environmental protection, etc. And it can provide a new method for the industrial extraction of baicalin.
