Chemical Constituents in Endophytic Fungus Nigrospora oryzae from Cordyceps
10.13422/j.cnki.syfjx.20191514
- VernacularTitle: 冬虫夏草内生真菌Nigrospora oryzae的化学成分分离鉴定
- Author:
Xiao-hua LI
1
;
Yu-mei CAO
1
;
Meng-ying JIN
1
;
Lei-qiang GONG
1
;
Da-le GUO
1
;
Yun DENG
1
Author Information
1. Key Laboratory of Standardization of Chinese Herbal Medicine Under Ministry of Education, State Key Laboratory and Breeding Base for Systematic Research Development and Utilization of Chinese Medical Resources, Co-founded by Sichuan Province and MOST, College Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China
- Publication Type:Research Article
- Keywords:
Cordyceps;
Nigrospora oryzae;
endophytic fungus;
mellein
- From:
Chinese Journal of Experimental Traditional Medical Formulae
2019;25(22):126-131
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the chemical constituents in theendophytic fungus Nigrospora oryzae from Cordyceps. Method: It was cultured with brownrice,and isolated and purified by chromatographic procedures, and the compounds were identified by NMR,ESI-MS and other spectral methods. Result: Totally 15 compounds were identified as mellein (1),linoleic acid (2),2-(2-hydroxyethyl)phenol (3),(3R)-mellein methyl ether (4),(3R,4S)-4-hydroxymellein (5),2-hydroxybenzaldehyde (6),3-phenylpropane-1,2-diol (7),1-phenyl-1,2-ethanediol (8),cyclo-(R-Prommmm-S-Ile) (9),cyclo-(D-Pro-L-Leu) (10),2-hydroxybenzaldehyde (11),4-hydroxy-8-O-methylmellein (12),cyclo-(S-Pro-S-Phe) (13),cyclo-(D-Pro-L-Ile) (14),cyclo-(D-Pro-L-Leu) (15). Conclusion: Compounds 1-15 were isolated from this fungus for the first time.