Influence factors of nucleoplasmic bridge frequencies in the peripheral blood lymphocytes of radiation workers
10.3760/cma.j.issn.0254-5098.2020.02.004
- VernacularTitle: 放射工作人员外周血淋巴细胞核质桥水平及其影响因素分析
- Author:
Xuelei TIAN
1
;
Xue LU
1
;
Jiangbin FENG
1
;
Yumin LYU
2
;
Mei TIAN
1
;
Qingjie LIU
1
Author Information
1. Key Laboratory of Radiological Protection and Nuclear Emergency, China CDC, National Institute for Radiological Protection, Chinese Center for Disease Control and Prevention, Beijing 100088, China
2. Laboratory of Toxicology, Henan Institution of Occupational Medicine, Zhengzhou 450052, China
- Publication Type:Journal Article
- Keywords:
Nucleoplasmic bridges;
Radiation worker;
Influence factors;
Ionizing radiation
- From:
Chinese Journal of Radiological Medicine and Protection
2020;40(2):94-98
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the effects of sex, age, length of service, type of work and annual effective radiation dose on nucleoplasmic bridge (NPB) in the peripheral blood lymphocytes of radiation workers.
Methods:The peripheral blood samples of 100 radiation workers in Henan province were collected and the NPB in peripheral blood lymphocytes were measured by CBMN assay. The frequencies of NPB formation and NPB-containing cells were calculated, and the effects of various factors on NPB incidence were analyzed statistically.
Results:The NPB frequency in radiation workers was higher than that in healthy people (Z=-8.123, P<0.01). Except for sex, the factors of age, length of service, type of work and annual effective dose had significant influences on NPB (χ2= 7.202-45.571, P<0.05).
Conclusions:NPB reflects the effect of low-dose long-term chronic irradiation on the occupational radiation workers.
