Research progress on correlation between antibiotic exposure in early life and childhood obesity
10.3760/cma.j.issn.2095-428X.2020.01.022
- VernacularTitle: 生命早期抗生素暴露与儿童肥胖相关性研究进展
- Author:
Yaqian WANG
1
;
Chonghuai YAN
2
Author Information
1. School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China
2. School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China;Ministry of Education-Shanghai Key Laboratory of Children′s Environmental Health, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China
- Publication Type:Review
- Keywords:
Early life;
Antibiotic exposure;
Child;
Obesity;
Intestinal flora
- From:
Chinese Journal of Applied Clinical Pediatrics
2020;35(1):78-80
- CountryChina
- Language:Chinese
-
Abstract:
Childhood obesity continues to be a public health concern worldwide, which seriously affects children′s health.In recent years, children have been generally exposed to low doses of antibiotics, and antibiotic problem has drawn international attention.Domestic and foreign researches show that antibiotic exposure in the early life of children is associated with childhood obesity risk, while its specific mechanism has not been completely clear.It is possible that antibiotics may lead to changes in the normal intestinal flora colonization of infants and young children and damage the early intestinal microflora, thus increasing the risk of childhood obesity, but further research is needed to confirm this causal mechanism.
