Solid -papillary carcinoma of the breast, an analysis of 44 cases 
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3760/cma.j.issn.1007-631X.2019.09.008
   		
        
        	
        		- VernacularTitle: 44例乳腺实性乳头状癌临床与病理学特征分析 
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Lili LIU
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Dingbao CHEN
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Siyuan WANG
			        		
			        		
			        		
			        			2
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Danhua SHEN
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. Department of Pathology, Peking University People′s Hospital, Beijing 100044, China
			        		
			        			2. Department of Breast Surgery, Peking University People′s Hospital, Beijing 100044, China
			        		
		        		
	        		
        		 
        	
        	
        	
        		- Publication Type:Journal Article
 
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Breast neoplasms;
			        		
			        		
			        		
				        		Pathology, clinical;
			        		
			        		
			        		
				        		Immunohistochemistry;
			        		
			        		
			        		
				        		Prognosis
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			Chinese Journal of General Surgery
	            		
	            		 2019;34(9):776-778
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	 Objective:To investigate the clinicopathological features of solid papillary carcinoma of the breast.
				        	
				        
				        	Methods:A retrospective study was performed to analyze the clinical and histopathologic manifestations in 44 cases of SPC in Peking University People′s Hospital from 2013.7 to 2017. 10.
				        	
				        
				        	Results:All the patients were female and mean age was 66.5 years. 17 cases complained of nipple discharge and 27 cases had breast mass .Pathologically tumors were of solid-papillary growth pattern. The tumor cells were polygonal or oval with mucin production and neuroendocrine differentiation. 22 cases were associated with invasive carcinoma, among which 15 cases were non-special invasive carcinomas. 7 cases were mucinous carcinoma.Six cases underwent modified radical mastectomy and axillary lymph nodes excision with two metastasis in an axillary lymph node.38 cases underwent breast conserving surgery or mastectomy. There were no local recurrence or distant metastasis during the follow-up periods of 12-48 months.
				        	
				        
				        	Conclusion:Solid papillary carcinoma of breast is a rare pathology type with predilection in older women. The postoperative prognosis is fair.